SLAMF1 antibody (FineTest®647)

Catalog No. ABIN7675522

The Rat Monoclonal anti-SLAMF1 antibody has been validated for FACS. It is suitable to detect SLAMF1 in samples from Mouse.

Quick Overview for SLAMF1 antibody (FineTest®647) (ABIN7675522)

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This SLAMF1 antibody is conjugated to FineTest®647

Application: Flow Cytometry (FACS)

Clone: TC15-12F12-2

Product Details anti-SLAMF1 Antibody (FineTest®647)

Purpose: FineTest®647 Anti-Mouse CD150/SLAM Antibody

Isotype: IgG2a, lambda

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 %BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: CD150

Background:

Synonyms: CD 150|Signaling lymphocytic activation molecule|Slam|Slamf1

Background: CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

Molecular Weight: 0

Gene ID: 27218

UniProt: Q9QUM4